Mutacin 1140: General-interest Articles (Click links below to view articles)
Better Homes and Gardens - Antibiotic Resistance
March, 2001 article discusses how germs can mutate and survive new antibiotics and medicines.
Antimicrobial Resistance Response to a Growing Problem
This statement from the National Institutes of Health discusses the emerging problem of antibiotic resistance.
Mutacin 1140: Scientific Articles (Click links below to view articles if available)
Hasper, H.E., Kramer, N.E., Smith, J.L., Hillman, J.D., Zachariah, C., Kuipers, O.P., de Kruijff, B. and Breukink, E. Cell wall precursor abduction as a novel antibiotic mechanism. Science, Submitted.
Smith, J.L., Orugunty, R., and Hillman, J.D. Lantibiotic Production by Streptococcus mutans: Their Uses in Replacement Therapy for the Prevention of Dental Caries and as Antibiotics for the Treatment of Various Infectious Diseases. Horizon Scientific Press, Rowan House, 28 Queens Road, Hethersett, Norwich, NR9 3DB, UK, in press.
Smith, L., Zachariah, C., Thirumoorthy, R., Rocca, J., Novák, J., Hillman, J.D. and Edison, A.S. 2003. Structure and dynamics of the lantibiotic mutacin 1140. Biochem. 42:10372-10384.
Smith L., Novák, J., Rocca J., McClung S., Hillman J.D. and Edison A.S. "Covalent Structure of Mutacin 1140 and a Novel Method for the Rapid Identification of Lantibiotics." Eur. J. Biochem. 2000;267:6810-6816.
Hillman J.D., Novák, J., Sagura E., Gutierrez J.A., Brooks T.A., Crowley P.J., Hess M., Azizi A., Leung K.P. Cvitkovitch D., and Bleiweis A.S.. "Genetic and Biochemical Analysis of Mutacin 1140, a Lantibiotic from Streptococcus mutans." Infection and Immunity 1998;66(6):2743-2749.
http://iai.asm.org
Hillman, J.D., Novák, J., Sagura, E., Gutierrez, J.A., Brooks, T.A., Crowley, P.J., Azziz, A., Leung, K.-P., Cvitkovitch, D., and Bleiweis, A.S. 1998. Genetic and biochemical analysis of mutacin 1140, a lantibiotic from Streptococcus mutans. Infect. Immun. 66:2743-2749.
Hillman, J.D., Yaphe, B.I., and Johnson, K.P. 1985. Colonization of the human oral cavity by a strain of Streptococcus mutans. J. Dent. Res. 64:1272-1274.
Hillman JD, Johnson KP, and Yaphe BI. "Isolation of a Streptococcus mutans Strain Producing a Novel Bacteriocin." Infection and Immunity 1984;44(1):141-144.
http://iai.asm.org
Hasper, H.E., Kramer, N.E., Smith, J.L., Hillman, J.D., Zachariah, C., Kuipers, O.P., de Kruijff, B. and Breukink, E. Cell wall precursor abduction as a novel antibiotic mechanism. Science, Submitted.
Mutacin 1140: Websites (Click links below to view articles if available)
Consumer Education: Antibiotics and Antibiotic Resistance:
Food and Drug Administration (FDA)
The FDA website has several articles and a video dealing with antibiotic resistance. An animated 9 minute video explaining how antimicrobial resistance both emerges and proliferates among bacteria on their website.
Articles:
The Battle of the Bugs: Fighting Antibiotic Resistance
Preserve a Treasure: Know When Antibiotics Work
An article form the Centers for Disease Prevention and the FDA PDF Brochure Here
A veces, el remedio es pero que la enfermedad
Is available only in Spanish and was produced by the Center for Disease Control and the FDA PDF Brochure Here
Center for Disease Control (CDC)
Articles:
Get Smart: Know When Antibiotics Work
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