How It Works
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When the ProBiora3® ingredient enters the mouth and contacts saliva, the freeze-dried probiotics activate and live, active bacteria attach themselves both on the surface of the teeth and deep beneath the gum line. These colonies become a basecamp of beneficial bacteria to support oral health. With daily replenishment, the ProBiora3 bacteria re-establish the natural microbial balance in the mouth and create whiter teeth, fresher breath and healthier teeth and gums.
In the oral cavity, harmful bacteria convert sugar and carbohydrates into lactic acid. Lactic acid is the bacterial byproduct which is responsible for dental caries and the erosion of tooth enamel. Without requiring lifestyle changes, the addition of the ProBiora3 probiotic ingredient can positively affect the long-term health and wellness of the mouth and the other health systems dependent on oral health. One unique strain of beneficial flora used in ProBiora3 is lactic-acid deficient and can promote healthy teeth. A byproduct of the other two strains is a natural low dose of hydrogen peroxide, which safely supports healthy gums, fresher breath and whiter teeth. Gum and Tooth HealthIf harmful, disease-causing bacteria are allowed to colonize in the periodontal pocket, the result is advanced periodontal disease. To address this, it is increasingly more common as well as very painful to have dentists clean teeth below the gum line. Research has revealed that even after the aggressive process of scaling to clean out the periodontal pockets, the future oral health of the patient is determined by the type of bacteria that colonizes first in the base of that clean pocket. If the harmful bacteria are first to colonize, the disease condition will quickly return. If the beneficial bacteria are first, then good oral health will be established and the dental office procedure will have been successful (Socransky and Hafajee, 1992, J. Perio, p. 322).ProBiora3 can provide a deep impact by rebalancing the oral flora in a simple, painless, non-invasive daily routine. No other consumer product impacts oral health below the gum line to get to the root of the problem. In clinical trials, twice-daily administration of Streptococcus rattus JH145™, S. oralis KJ3™ and S. uberis KJ2™ as combined in ProBiora3 substantially affected the levels of harmful bacteria in the mouth. The studies found that simply by using ProBiora3, the levels of harmful bacteria were reduced in plaque samples taken from below the gum line, at the bottom of the periodontal pocket. Existing mouthwashes and toothpastes that typically contain an antibacterial agent are able to only affect those areas of the mouth that the rinse is able to directly contact, which limits their effectiveness to contact with plaque above the gum line. Furthermore, the antibacterial agent is quickly washed from the mouth while the ProBiora3 bacteria have high substantivity; i.e., they have a prolonged duration of contact with disease-susceptible surfaces in the mouth and thus a prolonged beneficial activity. Oral care products and foods developed using this probiotic approach can safely maintain and promote oral health by normalizing the balance of the indigenous flora in favor of microorganisms associated with both healthy teeth and periodontal or gum tissues. Fresher BreathAntibacterial mouthwashes and breath fresheners promote killing up to 99.9% of bacteria and germs in the mouth. These products indiscriminately wipe out both the essential, good bacteria along with the harmful bacteria.Within several hours after using an antibacterial mouthwash or breath freshener, the surviving .1% of the bacteria remaining in the mouth will repopulate the full level of harmful bacteria that was present in the mouth before the product was used. This indiscriminate destruction of bacteria creates ongoing imbalances in the microflora that naturally inhabit the oral cavity. Antibacterial mouthwashes and breath fresheners simply mask the malodor and can never effectively address the issue on the causal level. Streptococcus oralis KJ3™ and Streptococcus uberis KJ2™ are natural antagonists to the malodor-creating bacteria, quickly colonizing to create a healthy balance of microflora and resulting in longer lasting, truly fresher breath. Whiter TeethA natural by-product of Streptococcus oralis KJ3™ and Streptococcus uberis KJ2™is a low-dose of hydrogen peroxide. As this good bacteria is replenished daily, it creates a gradual teeth whitening with the full benefits of long contact times, delivering 24 hour per day coverage of balancing and brightening.Yellowing, surface discoloration or staining are all results of lifestyle choices: tobacco use, coffee, tea, beets, etc. Anything that stains will affect the color of the teeth. Tooth enamel is porous, filled with microscopic cracks and pores that hold onto staining products. Commercial tooth whiteners employ extremely high levels of harsh, chemical hydrogen peroxide which can actually damage the tooth and create a roughness on the tooth's surface. This increases the film that builds up on the tooth surfaces and in the micro cracks and is available to hold on to stains. S. oralis KJ3 binds to the surface of the teeth, crowding out harmful bacteria by competing for the same nutrients and surface spaces. In laboratory studies, the low-dose hydrogen peroxide produced by the S. oralis KJ3 created a continuous whitening benefit that did not plateau over the duration of the study. With daily use, the colonization of S. oralis KJ3 provides a constant and expanding population for gradual and continual whitening effects. The hydrogen peroxide metabolites of S. oralis KJ3 also contribute to the breath-freshening features of the ProBiora3® blend by inhibiting the growth of harmful bacteria. The decrease in these harmful bacteria results in a substantial reduction in the volatile sulfur compounds associated with bad breath. Unlike other whitening products, ProBiora3 is completely safe for veneers, caps and dentures. |
Delivery Mechanisms
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